Download 2015 Nelson's Pediatric Antimicrobial Therapy by John S. Bradley, John D. Nelson et al. (eds.) PDF
By John S. Bradley, John D. Nelson et al. (eds.)
New twenty first Edition! This bestselling and standard source on pediatric antimicrobial therapy offers speedy entry to trustworthy, up to date options for therapy of all infectious ailments in little ones.
Practical, evidence-based options from the specialists in antimicrobial therapy
- Developed by means of exceptional editorial board
- Designed in case you look after young children and are confronted with judgements each day
- New at-a-glance tables of bacterial and fungal pathogen susceptibilities to universal antimicrobials
- New details on neonatal developmental pharmacology
- Includes remedy of parasitic infections and tropical medicine
- Updated exams in regards to the energy of the advice and the extent of facts for remedy techniques for significant infections
- Anti-infective drug directory, entire with formulations and dosages
- Antibiotic treatment for overweight children
- Antimicrobial prophylaxis/prevention of symptomatic infection
- Maximal grownup dosages and better dosages of a few antimicrobials conventional in children
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Additional resources for 2015 Nelson's Pediatric Antimicrobial Therapy
RECOMMENDED THERAPY FOR SELECTED NEWBORN CONDITIONS (cont) Therapy (evidence grade) Condition See Table 5B-D for neonatal dosages. Pulmonary infections (cont) Comments 12/19/14 3:39 PM – Pertussis72 Azithromycin 10 mg/kg PO, IV q24h for 5 days OR erythromycin ethylsuccinate PO for 14 days (AII) Association of erythromycin and pyloric stenosis in young infants; may also occur with azithromycin. Alternatives for >1 mo of age, clarithromycin for 7 days, and for >2 mo of age, TMP/SMX for 14 days. – P aeruginosa73 Ceftazidime IV, IM AND tobramycin IV, IM for ≥10–14 days (AIII) Alternatives: cefepime or meropenem, OR pip/tazo AND tobramycin – Respiratory syncytial virus74 Treatment: see Comments.
RECOMMENDED THERAPY FOR SELECTED NEWBORN CONDITIONS (cont) Therapy (evidence grade) Condition See Table 5B-D for neonatal dosages. Skin and soft tissues (cont) Comments 12/19/14 3:39 PM – S aureus17,75,77,87 MSSA: oxacillin/nafcillin IV, IM (AII) MRSA: vancomycin IV (AIII) Surgical drainage may be required. MRSA may cause necrotizing fasciitis. Alternatives for MRSA: clindamycin IV or linezolid IV. Convalescent oral therapy if infection responds quickly to IV therapy. htm. Evaluation and treatment do not depend on mother’s HIV status.
CMV-IVIG not recommended. – Perinatally or postnatally acquired23 Ganciclovir 12 mg/kg/day IV div q12h for 14–21 days (AIII) Antiviral treatment has not been studied in this population but can be considered in patients with acute, severe, visceral (end-organ) disease such as pneumonia, hepatitis, encephalitis, necrotizing enterocolitis, or persistent thrombocytopenia. If such patients are treated with parenteral ganciclovir, a reasonable approach is to treat for 2 wk and then reassess responsiveness to therapy.