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By Philip S. Mellor, Matthew Baylis, Christopher Hamblin, Charles H. Calisher, Peter P.C. Mertens

African horse illness virus is a double-stranded RNA virus which explanations a non-contagious, infectious arthropod-borne ailment of equines and sometimes canines. 9 specified, the world over recognized serotypes of the virus have thus far been pointed out. This booklet is predicated upon the findings of 2 programmes funded by way of the ecu fee. will probably be of worth not just to the expert study employees but in addition to veterinary employees facing regulate and to legislators looking to advertise secure foreign move of equines. the themes coated contain state of the art discussions on diagnostics, vaccines, molecular biology, vector reports, and epidemiology.

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In contrast to the vaccinated group, no boost 36 H. : AHSV in mules and donkeys in antibody titres were detected in sera collected from the second group of mules and donkeys after challenge. This result would suggest that the challenge virus was rapidly neutralised and did not initiate a replicating infection at the site of inoculation or in surrounding tissues. References 1. Baylis M, Hasnaoni H, Bouayoune H, Touti J, Mellor PS (1997) The spacial and seasonal distribution of African horse sickness and its potential Culicoides vectors in Morocco.

In: Walton TE, Osburn BI (eds) Bluetongue, African horse sickness and related orbiviruses. Proc 2nd Int Symp. CRC Press, Boca Raton, pp 825-831 8. Zientara S, Sailleau C, Moulay S, Wade-Evans A, Cruciere C (1995) Application of the polymerase chain reaction to the detection of African horse sickness viruses. J Virol Methods 53: 47-54 Authors' address: Dr. H. P. 13719, Casablanca, Morocco. Donkeys as reservoirs of African horse sickness virus c. , J. S. , P. S. , S. D. , P. R. , and P. Wohlsein2 2 !

7 approximately 100 ml of straw coloured fluid but there was no observed increase in peritoneal or pleural fluid, and the lungs appeared normal. Marked sub-epicardial haemorrhages were found over the left ventricle, which extended into the right ventricle. Haemorrhages were seen throughout the digestive tract, more particularly on the mucosae of the proventricular and pyloric regions of the stomach and the jejunum. Several mesenteric lymph nodes were haemorrhagic, often associated with haemorrhages in the mesenteric border of the bowel.

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